Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11732 |
JTV-519 hemifumarate
K201 hemifumarate |
MELK | PI3K/Akt/mTOR signaling |
JTV-519 hemifumarate,Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. | |||
T24239 |
K201
K-201,JTV 519,JTV-519,K 201 |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
K201 (JTV-519) 是一种 Ca2+ 依赖性阻滞剂,通过稳定兰尼碱受体来防止缺血性心脏和骨骼肌 (SkM) 中的肌质网异常 Ca(2+) 泄漏。 | |||
T11731 |
JTV-519 free base
K201 free base |
FLT | Angiogenesis; Tyrosine Kinase/Adaptors |
JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and serves as a partial agonist of ryanodine receptors in striated muscle. | |||
T11731L |
JTV-519 Formate
JTV-519 Formate (145903-06-6 Free base) |
Others; Calcium Channel | Membrane transporter/Ion channel; Metabolism; Others |
JTV-519 Formate 是一种 Ca2+ 依赖性的肌质网 Ca2+ 刺激的 ATP 酶 (SERCA) 阻断剂,同时也是横纹肌中兰尼碱受体 (ryanodine receptors) 的部分激动剂。JTV-519 Formate 显示出抗心律失常作用,是一种心脏保护剂。 |